inflamatory bowel disease

Introduction

Inflammatory bowel disease (IBD)

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

The main forms of inflammatory bowel disease (IBD) are Crohn’s disease and ulcerative colitis (UC). Inflammatory bowel diseases are considered autoimmune diseases, in which the body’s own immune system attacks elements of the digestive system.

Other forms of inflammatory bowel disease (IBD), which are not always classified as typical IBD:

  • Collagenous colitis
  • Lymphocytic colitis
  • Ischaemic colitis
  • Diversion colitis
  • Behçet’s disease
  • Indeterminate colitis

Symptoms of inflammatory bowel disease (IBD)

Inflammatory bowel disease (IBD) may present with any of the following symptoms: abdominal pain, vomiting, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss. Anemia is the most prevalent extraintestinal complication of inflammatory bowel disease. Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).

Complications of inflammatory bowel disease (IBD)

  • Inflammatory bowel disease may lead to one or more of the following complications:
  • Bowel obstruction
  • Ulcers (open sores) in digestive tract, mouth, anus, genital area
  • Bleeding
  • Fistulas
  • Anal fissure
  • Malnutrition
  • Colon cancer
  • Other health problems, such as arthritis, inflammation of the eyes or skin, clubbing of the fingernails, kidney stones, gallstones, and, occasionally, inflammation of the bile ducts. People with long-standing IBD also may develop osteoporosis, a condition that causes weak, brittle bones.

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The A1 Medical Center Treatment for inflammatory bowel disease (IBD)

The inflammatory bowel disease (IBD) treatment is unique because it focuses on repairing tissue damage and restoring function to improve each patient’s quality of life.

Patients are treated by minimally invasive local injection and/or by injecting the stem cells by intravenous implantation or by injecting them directly into the dammaged area, avoiding major surgical intervention in most cases.

Results

A more recently developed, less aggressive approach involves the use of mesenchymal stem cells (MSCs). Successful pre-clinical studies using MSCs in models of autoimmunity, inflammation or tissue damage have paved the way for clinical trials. Two phase I studies on autologous bone marrow-derived MSCs for the treatment of active refractory CD have been published recently; one using systemic administration in patients with luminal CD and the other assessing the effects of local injection of MSCs for the treatment of fistulizing CD, showing that application of autologous MSCs is feasible, well tolerated and might produce clinical benefits.

Patient Stories

Lavinia Conopan – 31 years old
“…I can now feel when I need to go to the toilet and my bladder capacity has increased…”

Ransom Doyle – 52 years old
“…I have been able to increase my distance walking to over 400+ meters with a cane and riding a two-wheel bicycle over a mile at a time…”

Rich Welsh – 27 years old
“…If you happen to have the chance of autologous stem cell treatment do not let it pass you by…”

Treatment Evaluation Process

In order to be evaluated for stem cell treatment, patients must complete an online medical history form. Once you’ve completed the online medical history and submitted it, a patient relations consultant will contact you. He or she will assist you with the rest of the evaluation process. Upon treatment approval, your consultant will also assist you with treatment scheduling and trip preparation.

List of diseases treated

image source: wikipedia

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